Associations between management factors and seroprevalence of Mycobacterium avium subsp. paratuberculosis in dromedary camels. (April 2022)

• Record Type: Journal Article
• Authors: Elmoslemany, Ahmed; Alanazi, Fahd; Elsohaby, Ibrahim; Fayez, Mahmoud; Alnaeem, Abdulmohsen
• Is Part Of: Comparative immunology, microbiology and infectious diseases. Volume 83(2022)
• Publication Date: 2022-04
• Subjects: Johne's disease -- Seroprevalence -- Risk factors -- ELISA -- Camels -- Saudi Arabia; Communicable diseases in animals -- Periodicals; Veterinary immunology -- Periodicals; Veterinary microbiology -- Periodicals; Immunology -- Periodicals; Microbiology -- Periodicals; Communicable diseases -- Periodicals; Communicable Diseases -- immunology -- Periodicals; Communicable Diseases -- veterinary -- Periodicals; Allergy and Immunology -- Periodicals; Microbiology -- Periodicals; Veterinary Medicine -- Periodicals; Immunologie -- Périodiques; Microbiologie -- Périodiques; Maladies infectieuses -- Périodiques; Communicable diseases; Immunology; Microbiology; Electronic journals; Periodicals; 636.08969
• DOI: 10.1016/j.cimid.2022.101780
• Languages: English
• ISSNs: 0147-9571

Abstract

Abstract: Johne's disease is a chronic infectious granulomatous enteritis caused by Mycobacterium avium subsp. paratuberculosis (MAP) and mainly infect wild and domestic animals. Although MAP infection has been reported worldwide, observational studies on MAP in camels are very scarce. The objective of the present investigation was to determine the herd- and camel-level seroprevalences and management factors associated with MAP seroprevalence in dromedary camels in the Eastern Province, Saudi Arabia. A cross-sectional study with two-stage random sampling was conducted. Serum samples from 391 camels in 67 herds were collected and tested for the presence of MAP antibodies using a commercial indirect ELISA test. The average MAP herd- and camel-level seroprevalences were 40.3% (95% CI: 29.10 – 52.60%) and 16.1% (95% CI: 12.78 – 20.11%), respectively. The herd-level factors showed a greater risk of MAP seropositivity in medium (36 − 75) and larger (>75) size herds compared with small (<36) herds. Furthermore, the risk of MAP seropositivity decreased in herds with calving pens compared to herds without calving pens. The camel-level factors indicated a decrease in seroprevalence of MAP with the age of camels. The present study revealed a high prevalence of MAP in dromedary camels in Eastern Province, Saudi Arabia. The herd-level risk factors for MAP seroprevalence identified in this study will provide the baseline data for developing and implementing a comprehensive control program for MAP in Saudi Arabia. Highlights: The average MAP herd- and camel-level seroprevalences were 40.3% and 16.1%, respectively. The risk of MAP seropositivity is higher in medium (36 – 75) and larger (>75) herds than in small (>36) herds. The risk of MAP seropositivity decreased in herds with calving pens compared to herds without calving pens. The camel-level factors indicated a decrease in seroprevalence of MAP with the age of camels.