Magnetic resonance non-echo planar diffusion-weighted imaging accuracy in detecting cholesteatoma in comparison with clinical and surgical findings. Issue 3 (18th March 2022)

• Record Type: Journal Article
• Authors: Al Zuhir, N; Zammit-Maempel, I; Yates, P; Dixon, J
• Is Part Of: Journal of laryngology & otology. Volume 136:Issue 3(2022)
• Page Start: 208
• Page End: 214
• Publication Date: 2022-03-18
• Subjects: Cholesteatoma -- Diagnosis -- Magnetic Resonance Imaging -- Diffusion Magnetic Resonance Imaging; Otolaryngology -- Periodicals; 617.51
• DOI: 10.1017/S0022215121002188
• Languages: English
• ISSNs: 0022-2151

Abstract

Abstract: Objective: Magnetic resonance imaging utilising non-echo planar diffusion-weighted imaging is known to have high sensitivity and specificity in detecting cholesteatoma. Method: Data was retrospectively collected from patients who had undergone non-echo planar diffusion-weighted imaging from 1 January 2010 to 31 December 2016. The ratio of average pixel grey-scale values between the middle-ear lesion, pons and temporal lobe was used to quantify the degree of restricted diffusion and assess the statistical significance to detect cholesteatoma. Results: A total of 107 patients had non-echo planar diffusion-weighted imaging during the study period. Non-echo planar diffusion-weighted imaging shows good specificity and sensitivity with an excellent positive predictive value and accuracy. Analysis of the grey-scale pixel ratio for cholesteatoma detection showed statistically significant results. Conclusion: Non-echo planar diffusion-weighted magnetic resonance imaging is accurate for cholesteatoma assessment. When the middle-ear lesion non-echo planar diffusion-weighted imaging intensity is higher than the ipsilateral temporal lobe, it is highly suggestive of a cholesteatoma formation.