A new antidiabetic and anti-inflammatory biflavonoid from Schinus polygama (Cav.) Cabrera leaves. Issue 5 (4th March 2022)

• Record Type: Journal Article
• Authors: El-Nashar, Heba A. S.; Mostafa, Nada M.; Eldahshan, Omayma A.; Singab, Abdel Nasser B.
• Is Part Of: Natural product research. Volume 36:Issue 5(2022)
• Page Start: 1182
• Page End: 1190
• Publication Date: 2022-03-04
• Subjects: biflavonoid -- Schinus polygama -- amylase -- anti-inflammatory -- membrane stabilization; Natural products -- Periodicals; Natural products -- Research -- Periodicals; Biological Factors -- Periodicals; Biological Products -- Periodicals; 547
• DOI: 10.1080/14786419.2020.1864365
• Languages: English
• ISSNs: 1478-6419

Abstract

Abstract: A new biflavonoid, luteolin-(6→8'')-apigenin was isolated from 80% methanol extract of Schinus polygama (Cav.) Cabrera leaves (Anacardiaceae). The structure was elucidated by 1D and 2D-NMR spectroscopic data. This compound exhibited in vitro antidiabetic effect via α -amylase assay. Furthermore, it possesses anti-inflammatory activity through membrane stabilization effect on erythrocytes. Graphical Abstract: UF0001