Biomimetic human bone marrow tissues: models to study hematopoiesis and platforms for drug testing. (2nd November 2021)
- Record Type:
- Journal Article
- Title:
- Biomimetic human bone marrow tissues: models to study hematopoiesis and platforms for drug testing. (2nd November 2021)
- Main Title:
- Biomimetic human bone marrow tissues: models to study hematopoiesis and platforms for drug testing
- Authors:
- García-García, Andrés
Martin, Ivan - Abstract:
- ABSTRACT: We propose an in vitro 3D culture system combining perfusion bioreactors, scaffolds and human primary cells to engineer fully-humanized, biomimetic and customizable bone marrow tissues. This system could serve as a model to investigate human hematopoietic stem cell niches, but also as a drug testing platform for pharmaceutical research and patient-personalized medicine.
- Is Part Of:
- Molecular & cellular oncology. Volume 8:Number 6(2021)
- Journal:
- Molecular & cellular oncology
- Issue:
- Volume 8:Number 6(2021)
- Issue Display:
- Volume 8, Issue 6 (2021)
- Year:
- 2021
- Volume:
- 8
- Issue:
- 6
- Issue Sort Value:
- 2021-0008-0006-0000
- Page Start:
- Page End:
- Publication Date:
- 2021-11-02
- Subjects:
- Engineered niches -- human hematopoiesis -- bone marrow -- drug testing
Tumors -- Periodicals
Neoplasms
Periodicals
616.99 - Journal URLs:
- http://www.tandfonline.com/loi/kmco20#.VyIIeFL2aic ↗
http://www.tandfonline.com/ ↗ - DOI:
- 10.1080/23723556.2021.2007030 ↗
- Languages:
- English
- ISSNs:
- 2372-3556
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 20977.xml