Targeting cancer's sweet spot: UGP2 as a therapeutic vulnerability. (2nd November 2021)
- Record Type:
- Journal Article
- Title:
- Targeting cancer's sweet spot: UGP2 as a therapeutic vulnerability. (2nd November 2021)
- Main Title:
- Targeting cancer's sweet spot: UGP2 as a therapeutic vulnerability
- Authors:
- Kim, Sunghoon
Wolfe, Andrew
Kim, Sung Eun - Abstract:
- ABSTRACT: Understanding the mechanisms governing metabolic reprogramming that underlie potential vulnerabilities in cancer cells is key to developing novel therapeutic strategies. The catalytic enzyme UDP-glucose pyrophosphorylase 2 (UGP2) drives the production of UDP-glucose. Our recent work demonstrated the crucial role of UGP2 in cancer growth and its regulation of cellular metabolic processes.
- Is Part Of:
- Molecular & cellular oncology. Volume 8:Number 6(2021)
- Journal:
- Molecular & cellular oncology
- Issue:
- Volume 8:Number 6(2021)
- Issue Display:
- Volume 8, Issue 6 (2021)
- Year:
- 2021
- Volume:
- 8
- Issue:
- 6
- Issue Sort Value:
- 2021-0008-0006-0000
- Page Start:
- Page End:
- Publication Date:
- 2021-11-02
- Subjects:
- UGP2 -- UDP-glucose -- YAP -- cancer metabolism -- glycosylation
Tumors -- Periodicals
Neoplasms
Periodicals
616.99 - Journal URLs:
- http://www.tandfonline.com/loi/kmco20#.VyIIeFL2aic ↗
http://www.tandfonline.com/ ↗ - DOI:
- 10.1080/23723556.2021.1990676 ↗
- Languages:
- English
- ISSNs:
- 2372-3556
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 20977.xml