A Case Report on Papillary Muscle Rupture Following Mitral Valve Replacement in the Setting of Previously Undiagnosed Amyloidosis. Issue 3 (8th March 2021)

• Record Type: Journal Article
• Authors: Choudhury, Nadim; Munoz Acuna, Ronny; Chaudhary, Omar; Chu, Louis; VanderLaan, Paul; Mahmood, Feroze; Sharkey, Aidan
• Is Part Of: A & A practice. Volume 15:Issue 3(2020)
• Page Start: e01415
• Publication Date: 2021-03-08
• Subjects: Analgesia -- Periodicals; Analgesia -- Case studies -- Periodicals; Anesthesiology -- Periodicals; Anesthesiology -- Case studies -- Periodicals; 617.9605
• DOI: 10.1213/XAA.0000000000001415
• Languages: English
• ISSNs: 2575-3126

Abstract

Abstract : Supplemental Digital Content is available in the text. Abstract : This case describes a patient who underwent mitral valve replacement (MVR) surgery with preservation of the subvalvular apparatus who suffered anterolateral papillary muscle rupture (PMR) postseparation from cardiopulmonary bypass. This patient had no history of coronary artery disease (CAD); subsequent pathology of the papillary muscle showed evidence of amyloid deposition. Although most PMRs are caused by ischemia from CAD, cardiac amyloidosis must be considered in the absence of CAD and worked up appropriately as cardiac involvement of amyloidosis, especially the amyloid light-chain (AL) subtype, is prognostic of increased mortality that can be mitigated with therapy.