Metal- and oxidant-free electrochemically promoted oxidative coupling of amines. Issue 1 (20th December 2021)

• Record Type: Journal Article
• Authors: Liu, Gang; Liu, Sen; Li, Zhen; Chen, Hengyu; Li, Jiashuai; Zhang, Yalin; Shen, Guodong; Yang, Bingchuan; Hu, Xiude; Huang, Xianqiang
• Is Part Of: RSC advances. Volume 12:Issue 1(2022)
• Page Start: 118
• Page End: 122
• Publication Date: 2021-12-20
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/d1ra07263c
• Languages: English
• ISSNs: 2046-2069

Abstract

Abstract : This paper presents a metal-free and external oxidant-free electrochemical method for the oxidative coupling methodology of amines in moderate to satisfactory yields. Abstract : The selective oxidation of amines into imines is a priority research topic in organic synthesis and has attracted much attention over the past few decades. However, the oxidation of amines generally suffers from the drawback of transition-metal, even noble-metal catalysts. Thus, the strategy of metal- and oxidant-free selective synthesis of imines is highly desirable yet largely unmet. This paper unravels a metal-free and external oxidant-free electrochemical strategy for the oxidative coupling methodology of amines. This general transformation is compatible with various functional amines and led to functionalized imines in moderate to satisfactory yields.