Protective Effects of Moderate Intensity Static Magnetic Fields on Diabetic Mice. Issue 8 (12th November 2020)

• Record Type: Journal Article
• Authors: Li, Qin; Fang, Yanwen; Wu, Ningzi; Gu, Lili; Li, Hongxing; Liao, Zhongcai; Liu, Mengyu; Fang, Zhicai; Zhang, Xinyue
• Is Part Of: Bioelectromagnetics. Volume 41:Issue 8(2020:Dec.)
• Page Start: 598
• Page End: 610
• Publication Date: 2020-11-12
• Subjects: alloxan -- blood glucose -- diabetes -- static magnetic field -- STZ; Electromagnetism -- Physiological effect -- Periodicals; 571.47
• DOI: 10.1002/bem.22305
• Languages: English
• ISSNs: 0197-8462

Abstract

Abstract : The purpose of this study was to investigate the effects of moderate‐intensity static magnetic field (SMF) on diabetic mice. We studied the effects of SMF on blood glucose of normal mice by starch tolerance and glucose tolerance tests. Then, we evaluated the effects of SMF on blood glucose of diabetic mice by establishing alloxan‐induced type 1 diabetic mice and high‐fat diet + streptozotocin (STZ)‐induced type 2 diabetic mice. The results showed that different magnetic field intensities and blank control did not affect the blood glucose of normal mice. After starch and glucose administration, different magnetic fields could improve the glucose tolerance of normal mice, and this was obvious in the 600 mT group. In the experiment of type 1 diabetic mice induced by alloxan, the results showed that different magnetic field intensities could improve the starch tolerance of mice, and that in the 400 mT group was obvious. In the experiment of type 2 diabetic mice induced by a high‐fat diet + STZ, the 400 mT group could reduce food intake and water consumption in the later period. The 600 mT group could improve the starch tolerance of mice. The 400 and 600 mT groups could reduce fasting blood glucose. At the same time, total cholesterol and triglyceride decreased in different magnetic field intensities, and the 600 mT group could significantly increase the serum insulin content of mice. In summary, the results of this study suggest that SMF has a protective role in diabetic mice. Bioelectromagnetics. © 2020 Bioelectromagnetics Society