Intraindividual variability in sleep schedule: effects of an internet-based cognitive-behavioral therapy for insomnia program and its relation with symptom remission. Issue 12 (8th June 2020)

• Record Type: Journal Article
• Authors: Shaffer, Kelly M; Hedeker, Donald; Morin, Charles M; Ingersoll, Karen; Thorndike, Frances; Ritterband, Lee M
• Is Part Of: Sleep. Volume 43:Issue 12(2020)
• Publication Date: 2020-06-08
• Subjects: cognitive therapy -- internet -- intraindividual variability -- risk factors -- personalized medicine -- sleep initiation and maintenance disorders -- treatment outcome; Sleep -- Physiological aspects -- Periodicals; Sleep disorders -- Periodicals; Sommeil -- Aspect physiologique -- Périodiques; Sommeil, Troubles du -- Périodiques; Sleep disorders; Sleep -- Physiological aspects; Sleep -- physiological aspects; Sleep Wake Disorders; Psychophysiology; Electronic journals; Periodicals; 616.8498
• DOI: 10.1093/sleep/zsaa115
• Languages: English
• ISSNs: 0161-8105

Abstract

Abstract: Study Objectives: Sleep schedule consistency is fundamental to cognitive-behavioral therapy for insomnia (CBT-I), although there is limited evidence suggesting whether it predicts treatment response. This analysis tested whether: (1) an Internet-based CBT-I program affects intraindividual variability (IIV) in sleep schedule and (2) sleep schedule IIV predicts insomnia symptom remission. Methods: This secondary analysis compares participants ( N = 303) randomized to an Internet-based CBT-I program (SHUTi—Sleep Healthy Using the Internet) or Internet-based patient education (PE). Participants reported daily bedtimes and rising times on 10 online sleep diaries collected over 2 weeks at baseline and 9-week post-intervention assessment. Participants completed the Insomnia Severity Index (ISI) at post-assessment and 6-month follow-up; symptom remission was defined by ISI < 8. Mixed effects location scale modeling was used to examine the effect of SHUTi on bedtime and rising time IIV; a novel two-staged analysis examined the effect of bedtime and rising time IIV on insomnia symptom remission. Results: At post-assessment, SHUTi participants reported about 30% less bedtime and 32% less rising time variability compared to PE ( p s < 0.03). Bedtime and rising time IIV was not independently associated with likelihood of insomnia symptom remission at the subsequent time point ( p s > 0.18), nor did sleep schedule IIV moderate treatment response ( p s > 0.12). Conclusions: Findings demonstrate that an Internet-delivered CBT-I program can effectively increase users' sleep schedule consistency relative to an educational control. This consistency, however, was not related to treatment outcome when defined by insomnia symptom remission, suggesting that enforcing rigid sleep schedules for patients may not be necessary for treatment success. Clinical Trial Registration: NCT00328250