Implicit-statistical learning in aphasia and its relation to lesion location. (October 2020)

• Record Type: Journal Article
• Authors: Vadinova, Veronika; Buivolova, Olga; Dragoy, Olga; van Witteloostuijn, Merel; Bos, Laura S.
• Is Part Of: Neuropsychologia. Volume 147(2020)
• Publication Date: 2020-10
• Subjects: Statistical learning -- Implicit learning -- Aphasia -- Stroke -- Syntax -- Grammar; Neuropsychology -- Periodicals; Neurology -- Periodicals; Psychophysiology -- Periodicals; Neuropsychologie -- Périodiques; Neuropsychology; Periodicals; Electronic journals; 616.8
• DOI: 10.1016/j.neuropsychologia.2020.107591
• Languages: English
• ISSNs: 0028-3932

Abstract

Abstract: Background: Implicit-statistical learning (ISL) research investigates whether domain-general mechanisms are recruited in the linguistic processes that require manipulation of patterned regularities ( e.g. syntax). Aphasia is a language disorder caused by focal brain damage in the left fronto-temporal-parietal network. Research shows that people with aphasia (PWA) with frontal lobe lesions manifest convergent deficits in syntax and ISL mechanisms. So far, ISL mechanisms in PWA with temporal or parietal lobe lesions have not been systematically investigated. Aims: We investigated two complementary hypotheses: 1) the anatomical hypothesis, that PWA with frontal lesions display more severely impaired ISL abilities than PWA with posterior lesions and 2) the behavioural hypothesis, that the magnitude of impairment in ISL mechanisms correlates to syntactic deficits in aphasia. Methods: We tested 13 PWA, 5 with frontal lesions and 8 with posterior lesions, and 11 non-brain-damaged controls on a visual statistical learning (VSL) task. In addition, all PWA completed several linguistic tasks. Reaction times, obtained in the VSL task, were analyzed using linear mixed-effects model. Correlational statistics were used to assess the relationship between VSL task performance and linguistic measures. Results and Discussion: We did not find support for the anatomical hypothesis as patients with spared frontal regions also manifested impaired ISL mechanisms. This is attributed to a) ISL mechanisms being vulnerable to other cognitive dysfunctions and/or b) ISL mechanisms anatomically extending to the posterior brain regions. Notably, ISL mechanisms were impaired, but not absent in aphasia. With regards to the behavioural hypothesis, we provide empirical evidence of correlation between ISL mechanisms and syntactic, but not lexical impairment in aphasia. We discuss both the theoretical contributions to the debate of domain-independence of ISL mechanisms and clinical implications for implicit language therapy. Highlights: We tested implicit-statistical learning in patients with aphasia and frontal or posterior lesions. Implicit-statistical learning is impaired but not completely absent in aphasia. Lesion location does not predict implicit-statistical learning deficit in aphasia. The magnitude of learning effect weakly correlates to the degree of impairment in syntax.