Multifunctional fluorescent "Off-On-Off" nanosensor for Au3+ and S2− employing N-S co-doped carbon–dots. (November 2018)

• Record Type: Journal Article
• Authors: Sharma, Vinay; Kaur, Navpreet; Tiwari, Pranav; Saini, Anoop K.; Mobin, Shaikh M.
• Is Part Of: Carbon. Volume 139(2018)
• Page Start: 393
• Page End: 403
• Publication Date: 2018-11
• Subjects: Carbon -- Periodicals; Carbone -- Périodiques; Koolstof; Toepassingen; Electronic journals; 546.681
• DOI: 10.1016/j.carbon.2018.07.004
• Languages: English
• ISSNs: 0008-6223

Abstract

Abstract: Out of the plethora of sensors being developed using carbon dots, the use of green alternatives with the potential of multi-functionality is still in its infancy. In view of this, the present work shows the use of Rosa indica derived heteroatom i.e. nitrogen and sulfur co-doped rose carbon dot (N-S@RCD ) for dual fluorescence based sensing of multi-analytes. The N-S@RCD shows interesting fluorescence turn "off-on-off" response towards S 2− and Au 3+ with limit of detection (LOD) 92.4 nM and 63.1 nM, respectively. To the best of our knowledge, this is first report on direct "Turn-on" of c-dots with S 2− ions without any intermediate c-dot–quencher complex. Further, the bioimaging and flow cytometry studies revealed the potential of live cell imaging, intracellular sensing and cytocompatibility of N-S@RCD . The hemocompatibility of N-S@RCD was also investigated for potential in vivo applications. Moreover, the "off-on-off" fluorescence behaviour was used to construct molecular logic gates which simulate single input logic "YES" and multi-input "INHIBIT" logic system. Graphical abstract: Image 1