A novel Hemi-Body Irradiation technique using electron beams (HBIe−). (February 2018)

• Record Type: Journal Article
• Authors: Delinikolas, Panagiotis; Patatoukas, Georgios; Kouloulias, Vasilios; Dilvoi, Maria; Plousi, Agapi; Efstathopoulos, Efstathios; Platoni, Kalliopi
• Is Part Of: Physica medica. Volume 46(2018)
• Page Start: 16
• Page End: 24
• Publication Date: 2018-02
• Subjects: Half-body skin irradiation -- Stanford technique -- Kaposi's sarcoma -- T-cell lymphoma; Medical physics -- Periodicals; Biophysics -- Periodicals; Biophysics -- Periodicals; Imagerie médicale -- Périodiques; Radiothérapie -- Périodiques; Rayons X -- Sécurité -- Mesures -- Périodiques; Physique -- Périodiques; Médecine -- Périodiques; 610.153
• DOI: 10.1016/j.ejmp.2017.12.022
• Languages: English
• ISSNs: 1120-1797

Abstract

Highlights: A half body skin irradiation technique is presented. Practical range at 2 g/cm 2 for optimal depth target coverage. 7% variation of the delivered dose over the target area. Average delivered versus prescribed dose differed by less than 2%. Protection of healthy skin. Abstract: Purpose: Certain radiation responsive skin diseases may develop symptoms on the upper or the lower half of the body. The concept of a novel Hemi-Body Electron Irradiation (HBIe − ) technique, described in this work, provides a low cost, LINAC based, intermediate treatment option in between extremely localized and Total Skin irradiation techniques. Materials and methods: The HBIe − technique, developed in our department, incorporates a custom crafted treatment chamber equipped with adjustable Pb shielding and a single electron beam in extended Source-Skin Distance (SSD) setup. The patient is positioned in 'Stanford' technique positions. The geometrical setup provides both optimal dose homogeneity and dose deposition up to a depth of 2 cm. To confirm this, the following characteristics were measured and evaluated: a) percentage depth dose (PDD) on the treatment plane produced by a single electron beam at perpendicular incidence for six fields at 'Stanford' angles, b) 2D profile of the entrance dose on the treatment plane produced by a single field and c) the total surface dose on an anthropomorphic phantom delivered by all 6 fields. Results: The resulting homogeneity of the surface dose in the treatment plane for an average patient was 5–6%, while surface dose homogeneity on the anthropomorphic phantom was 7% for both the upper and the lower HBIe − variants. The total PDD exhibits an almost linear decrease to a practical range of 2 g/cm 2 . Conclusion: In conclusion, HBIe − was proven effective in delivering the prescribed dose to the target area, while protecting the healthy skin.