Bloodstream infection by multidrug‐resistant Streptococcus oralis in a leukemic patient with febrile neutropenia after hematopoietic stem cell transplantation. Issue 2 (20th January 2020)

• Record Type: Journal Article
• Authors: Watanabe, Noriyuki; Kobayashi, Kiyoko; Koyama, Sachie; Tabira, Mayu; Matsuno, Junpei; Taji, Yoshitada; Akuzawa, Yu; Ishikawa, Maho; Maeda, Tomoya; Imai, Kazuo; Tarumoto, Norihito; Asou, Norio; Mitsutake, Kotaro; Ebihara, Yasuhiro
• Is Part Of: Transplant infectious disease. Volume 22:Issue 2(2020)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2020-01-20
• Subjects: bloodstream infection -- febrile neutropenia -- multidrug resistance -- Streptococcus oralis -- teicoplanin; Transplantation of organs, tissues, etc -- Complications -- Periodicals; Communicable diseases -- Periodicals; Infection -- Periodicals; 617.01
• DOI: 10.1111/tid.13246
• Languages: English
• ISSNs: 1398-2273

Abstract

Abstract: We reported the case of a patient with leukemia who developed febrile neutropenia after hematopoietic stem cell transplantation. Blood culture results revealed the presence of Streptococcus oralis, while antimicrobial susceptibility testing showed the resistance to penicillin and cephem. Furthermore, isolates were not susceptible to either meropenem or daptomycin but not to vancomycin. S oralis is known to belong to Streptococcus mitis group and be a causative agent of bacteremia in the neutropenic patients, but multidrug resistance of S oralis is rare. Our findings suggest that we might pay attention to the emergence of the microorganisms acquiring multidrug resistance in neutropenic patients.