Directed CH Alkenylation of Quinoline N‐Oxides at the C‐8 Position Using a Cationic Rhodium(I) Catalyst. Issue 7 (30th April 2014)

• Record Type: Journal Article
• Authors: Shibata, Takanori; Matsuo, Yusuke
• Is Part Of: Advanced synthesis & catalysis. Volume 356:Issue 7(2014)
• Page Start: 1516
• Page End: 1520
• Publication Date: 2014-04-30
• Subjects: alkenylation -- CH activation -- directing group -- N‐oxides -- rhodium catalysts; Catalysis -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Chemistry -- Periodicals; Chemistry, Technical -- Periodicals; Chemistry -- Periodicals; Catalysis -- Periodicals; Technology, Pharmaceutical -- Periodicals; 547.2
• DOI: 10.1002/adsc.201400223
• Languages: English
• ISSNs: 1615-4150

Abstract

Abstract: The cationic rhodium‐catalyzed alkenylation proceeds at the C‐8 position of quinoline N ‐oxides. Regioselective CH bond activation was achieved by the directing effect of the anionic oxygen of an N ‐oxide moiety, which can be readily removed by reductive treatment. A variety of 8‐alkenylated quinoline N ‐oxides was obtained in moderate to high yields. Abstract :