Visible Light‐Induced Regioselective Decarboxylative Alkylation of the C(sp2)−H Bonds of Non‐Aromatic Heterocycles. Issue 17 (19th July 2019)

• Record Type: Journal Article
• Authors: Liu, Lixin; Pan, Neng; Sheng, Wei; Su, Lebin; Liu, Long; Dong, Jianyu; Zhou, Yongbo; Yin, Shuang‐Feng
• Is Part Of: Advanced synthesis & catalysis. Volume 361:Issue 17(2019)
• Page Start: 4126
• Page End: 4132
• Publication Date: 2019-07-19
• Subjects: photoredox catalysis -- decarboxylative alkylation -- NHPI esters -- sunlight -- non-aromatic heterocycles; Catalysis -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Chemistry -- Periodicals; Chemistry, Technical -- Periodicals; Chemistry -- Periodicals; Catalysis -- Periodicals; Technology, Pharmaceutical -- Periodicals; 547.2
• DOI: 10.1002/adsc.201900572
• Languages: English
• ISSNs: 1615-4150

Abstract

Abstract: With sunlight or blue LEDs irradiation, regioselective decarboxylative alkylation of various non‐aromatic heterocycles has been realized via C( sp 3 )‐centered radical C( sp 2 )−C( sp 3 ) bond formation under oxidant‐free conditions at room temperature. This reaction readily incorporates various functional alkyl groups into heterocyclic compounds without observation of any alkyl radical rearrangement and represents a mild and general tool for the preparation of valuable alkyl group‐functionalized heterocyclic compounds. Abstract :