Administration of rectal cytotec versus rectal buscopan before hysteroscopy. Issue 1 (3rd January 2022)

• Record Type: Journal Article
• Authors: Gokmen Karasu, Ayse Filiz; Aydin, Serdar; Ates, Seda; Takmaz, Taha; Comba, Cihan
• Is Part Of: Minimally invasive therapy & allied technologies. Volume 31:Issue 1(2022)
• Page Start: 94
• Page End: 98
• Publication Date: 2022-01-03
• Subjects: Hysteroscopycervical priming pain hyoscine-n-butyl bromide -- misoprostol; Endoscopy -- Periodicals; Interventional radiology -- Periodicals; Endoscopic surgery -- Periodicals; 617.05
• DOI: 10.1080/13645706.2020.1748059
• Languages: English
• ISSNs: 1364-5706

Abstract

Abstract: Introduction: Our objective was to compare the effect of rectal misoprostol (Cytotec) versus rectal hyoscine-n-butyl bromide (Buscopan) on patients undergoing hysteroscopy. We hypothesised that HBB may have a role in cervical priming. Material and methods: This trial was conducted at Bezmialem Vakif University Hospital. Women of reproductive age between 18–50 years who were scheduled for operative hysteroscopy indicated by type 1 submucous myoma or endometrial polyps were recruited for the study. Ninety patients were divided randomly into three groups. Group 1 received placebo treatment. Group 2 received rectal 200 mcg misoprostol and Group 3 received rectal 20 mg hyoscine-n-butyl bromide two hours before the procedure. Procedures were performed using a bipolar 26 F (9 mm) continuous-flow rigid resectoscope with a 30° lens. The outcome measures included cervical dilation width and time, ease of cervical dilation, procedure time and operative complications. Postoperative self-rated pain was assessed one hour after the procedure. Results: Thirteen patients (43. 3%) in the placebo treatment group, 11 patients (36.7%) in the misoprostol group and four patients (13.3%) in the hyoscine-n-butyl bromide group needed analgesics postoperatively ( p = .02). The mean duration of cervical dilation time was longest in Group 1 and shortest in Group 3, however this difference did not reach statistical significance ( p =.11). There was no difference with regard to other studied parameters. Summary: HBB reduced the need for pain medication compared to placebo. Larger studies are needed to further investigate the role of HBB in facilitating pre-operative cervical priming.