Quetiapine Relieved Pisa Syndrome in Patient With Parkinson Disease. Issue 6 (November 2020)

• Record Type: Journal Article
• Authors: Zhao, Junwu; Wang, Quan; Sun, Hairong; Liu, Xiaoxiao; Leng, Bing; Wang, Tong
• Is Part Of: Clinical neuropharmacology. Volume 43:Issue 6(2020)
• Publication Date: 2020-11
• Subjects: Pisa syndrome -- quetiapine -- Parkinson disease; Neuropharmacology -- Periodicals; 615.78
• DOI: 10.1097/WNF.0000000000000416
• Languages: English
• ISSNs: 0362-5664

Abstract

Abstract : Objectives: The aim of the study was to report quetiapine-relieved Pisa syndrome in a patient with Parkinson disease and to discuss the pathogenesis and treatment of Pisa syndrome. Methods: We report a 74-year-old female patient with a history of Parkinson disease for 7 years. Pisa syndrome, lateral deviation of the spine and leaning to one side, appeared more than a year ago; adjusting levodopa was ineffective. After treatment with quetiapine for visual hallucinations, the patient's right side tilt was completely relieved after taking the drug for 1 month. Conclusions: Drug-related Pisa syndrome may be associated with the imbalance in dopamine-choline. Pisa syndrome may have similar mechanisms and treatment options to dystonia. This is the first report of quetiapine relieving Pisa syndrome in a patient with Parkinson disease.