A Case of Sulfhemoglobinemia Secondary to a Urinary Tract Infection. Issue 8 (November 2020)

• Record Type: Journal Article
• Authors: Campagna, Giovanni; Espaillat, Andre; Pfeiffer, Thomas; Powers, Jacquelyn M.; McClure, Meghan; Hess, Lauren M.
• Is Part Of: Journal of pediatric hematology/oncology. Volume 42:Issue 8(2020)
• Publication Date: 2020-11
• Subjects: sulfhemoglobinemia -- urinary tract infection -- spina bifida -- E. coli -- blood transfusion; Pediatric hematology -- Periodicals; Tumors in children -- Periodicals; 618.9215
• DOI: 10.1097/MPH.0000000000001591
• Languages: English
• ISSNs: 1077-4114

Abstract

Abstract : Sulfhemoglobinemia (SulfHb) is a rare dyshemoglobinemia that can present with cyanosis in the absence of respiratory distress. It has been reported secondary to drug ingestion and chronic constipation. We present a case of SulfHb in an adolescent female with spina bifida and neurogenic bladder in the setting of an Escherichia coli urinary tract infection. An arterial blood gas differentiated a dyshemoglobinemia from other causes of hypoxemia. The resolution was achieved with antibiotics and red cell transfusion. Here we review the pathophysiology of SulfHb and contribute a unique case report to the limited body of literature on this topic.