Comparing Image Segmentation Techniques for Determining 3D Orbital Cavernous Hemangioma Size on MRI. Issue 6 (November 2020)

• Record Type: Journal Article
• Authors: Boparai, Ranjodh S.; Maeng, Michelle M.; Dunbar, Kristen E.; Godfrey, Kyle J.; Tooley, Andrea A.; Maher, Mary; Kazim, Michael
• Is Part Of: Ophthalmic plastic and reconstructive surgery. Volume 36:Issue 6(2020)
• Publication Date: 2020-11
• Subjects: Eye -- Surgery -- Periodicals; Ophthalmic plastic surgery -- Periodicals; Reconstructive Surgical Procedures -- Periodicals; Ophthalmologic Surgical Procedures -- Periodicals; Ophthalmology -- Periodicals; Surgery -- Periodicals; 617.70592
• DOI: 10.1097/IOP.0000000000001651
• Languages: English
• ISSNs: 0740-9303

Abstract

Abstract : Purpose: To measure orbital cavernous hemangioma size using 3 segmentation methods requiring different degrees of subjective judgment, and to evaluate interobserver agreement using these methods. Methods: Fourteen patients with orbital cavernous hemangiomas were included in the study. Pretreatment T2-weighted MRIs were analyzed by 2 observers using 3 methods, including 1 user-dependent image segmentation method that required high degrees of subjective judgment (ellipsoid) and 2 parameter-dependent methods that required low degree of subjective judgment (GrowCut and k -means clustering segmentation). Interobserver agreement was assessed using Lin's concordance correlation coefficients. Results: Using the ellipsoid method, the average tumor sizes calculated by the 2 observers were 1.68 ml (standard deviation [SD] 1.45 ml) and 1.48 ml (SD 1.19 ml). Using the GrowCut method, the average tumor sizes calculated by the 2 observers were 3.00 ml (SD 2.46 ml) and 6.34 ml (SD 3.78 ml). Using k -means clustering segmentation, the average tumor sizes calculated by the 2 observers were 2.31 ml (SD 1.83 ml) and 2.12 ml (SD 1.87 ml). The concordance correlation coefficient for the ellipsoid, GrowCut, and k -means clustering methods were 0.92 (95% CI, 0.83–0.99), 0.12 (95% CI, –0.21 to 0.44), and 0.95 (95% CI, 0.90–0.99), respectively. Conclusions: k -means clustering, a parameter-dependent method with low degree of subjective judgment, showed better interobserver agreement compared with the ellipsoid and GrowCut methods. k -means clustering clearly delineated tumor boundaries and outlined components of the tumor with different signal intensities. Abstract : k -means clustering, a parameter-dependent image segmentation method with low degree of subjective judgment, showed better interobserver agreement compared with user-dependent image segmentation methods when measuring orbital cavernous hemangioma tumor size.