759 RELATIONSHIP BETWEEN G8 AND CFS IN A COHORT OF LUNG CANCER PATIENTS REFERRED TO A SPECIALISED ONCO-GERIATRIC CLINIC. (8th March 2022)

• Record Type: Journal Article
• Authors: Dunnett-Kane, V; Ayrton, L; Ng, C
• Is Part Of: Age and ageing. Volume 51(2022)Supplement 1
• Publication Date: 2022-03-08
• Subjects: Aging -- Periodicals; Geriatrics -- Periodicals; 618.97
• DOI: 10.1093/ageing/afac037.759
• Languages: English
• ISSNs: 0002-0729

Abstract

Abstract: Introduction: The International Society of Geriatric Oncology recommends using screening tools to identify cancer patients who would benefit from a comprehensive geriatric assessment. G8, a tool specifically designed for oncology, has been well validated in this setting (1). Rockwood Clinical frailty score (CFS) is a widely used tool to assess frailty, and has been adopted into standard assessments at many sites (2). However, this tool is less well validated in patients with cancer. Methods: In this single site observational study we recorded CFS and G8 in 89 patients with lung cancer referred to a local onco-geriatrics clinic between 21/10/20 and 5/2/21. Both scores were available for 82 patients. We aimed to measure the correlation between G8 and CFS in this cohort. Results: G8 score ≤ 14 is a referral criteria for the clinic, therefore 100% (82/82) of patients were classified as 'frail' using G8. Of these, only 23.2% (19/82) were classified as 'mildly frail' or worse using CFS (scores ≥5). Using Spearman's rank correlation we found a very weak/negligible negative correlation between CFS and G8 (−0.2519, p = 0.0224). Conclusion: The small proportion of patients (23.2%) classified as frail by CFS suggests that a G8 cut off of 14 may overestimate frailty. Previous work by our group has found that using a cut off of 13 is better able to predict chemotherapy outcomes(3). However, considering the lack of evidence for CFS in oncology, this poor correlation between G8 and CFS may question the usefulness of CFS in this context. (1) Decoster L, Puyvelde K, Mohile S, et al. Ann Oncol. 2015 Feb; 26(2): 288–300 (2) NHS Elect. [Online].; 2018 [cited 16/2/21] (3) A. Tivey, M. Ullah, A. Beech, et al. J Geriatr Oncol. 2020 Mar; 11(7).