Tackling Hypotheticals in Helminth Genomes. Issue 3 (March 2018)

• Record Type: Journal Article
• Authors: Palevich, Nikola; Britton, Collette; Kamenetzky, Laura; Mitreva, Makedonka; de Moraes Mourão, Marina; Bennuru, Sasisekhar; Quack, Thomas; Scholte, Larissa Lopes Silva; Tyagi, Rahul; Slatko, Barton E.
• Is Part Of: Trends in parasitology. Volume 34:Issue 3(2018)
• Page Start: 179
• Page End: 183
• Publication Date: 2018-03
• Subjects: hypothetical genes -- annotation -- helminth -- genomes -- RNAi -- CRISPR; Parasitology -- Periodicals; Parasitology -- Periodicals; Biology -- Periodicals; Parasitology; Biology; Parasitologie -- Périodiques; Online resources; 571.999
• DOI: 10.1016/j.pt.2017.11.007
• Languages: English
• ISSNs: 1471-4922

Abstract

Abstract : Advancements in genome sequencing have led to the rapid accumulation of uncharacterized 'hypothetical proteins' in the public databases. Here we provide a community perspective and some best-practice approaches for the accurate functional annotation of uncharacterized genomic sequences.