Occupational risk of SARS-CoV-2 infection and reinfection during the second pandemic surge: a cohort study. Issue 2 (8th December 2021)

• Record Type: Journal Article
• Authors: Leidi, Antonio; Berner, Amandine; Dumont, Roxane; Dubos, Richard; Koegler, Flora; Piumatti, Giovanni; Vuilleumier, Nicolas; Kaiser, Laurent; Balavoine, Jean-François; Trono, Didier; Pittet, Didier; Chappuis, François; Kherad, Omar; Courvoisier, Delphine Sophie; Azman, Andrew S; Zaballa, Maria Eugenia; Guessous, Idris; Stringhini, Silvia
• Other Names: author non-byline.; Alber Victoria author non-byline.; Arm-Vernez Isabelle author non-byline.; Azman Andrew S author non-byline.; Bachmann Delphine author non-byline.; Bachmann Donatien author non-byline.; Baggio Stéphanie author non-byline.; Balavoine Jean-François author non-byline.; Monteiro Gil Barbosa author non-byline.; Baysson Hélène author non-byline.; Bleich Patrick author non-byline.; Boissel Isabelle author non-byline.; Chappuis François author non-byline.; Collombet Prune author non-byline.; Courvoisier Delphine author non-byline.; Couson Philippine author non-byline.; Davidovic Alioucha author non-byline.; Deiri Clement author non-byline.; Rio Divina Del author non-byline.; Mestral Carlos de author non-byline.; Ridder David De author non-byline.; Dibner Yaron author non-byline.; D'Ippolito Paola author non-byline.; Duc Joséphine author non-byline.; Dumont Roxane author non-byline.; Eckerle Isabella author non-byline.; Merjani Nacira El author non-byline.; Ferniot Gwennaelle author non-byline.; Flahault Antonie author non-byline.; Francioli Natalie author non-byline.; Frangville Marion author non-byline.; Garande Carine author non-byline.; Gétaz Laurent author non-byline.; Giraldo Pamela author non-byline.; Golaz Fanny author non-byline.; Guérin Julie author non-byline.; Guessous Idris author non-byline.; Haboury Ludivine author non-byline.; Harnal Séverine author non-byline.; Javet Victoria author non-byline.; Kaiser Laurent author non-byline.; Kherad Omar author non-byline.; Laboulais Amélie author non-byline.; Lamour Gaëlle author non-byline.; Lefebvre Xavier author non-byline.; Lescuyer Pierre author non-byline.; Loizeau Andrea Jutta author non-byline.; Lombard Fanny-Blanche author non-byline.; Lorthe Elsa author non-byline.; Martinez Chantal author non-byline.; Massiha Kourosh author non-byline.; Metral-Boffod Ludovic author non-byline.; Meyer Benjamin author non-byline.; Mostaguir Khaled author non-byline.; Nehme Mayssam author non-byline.; Noël Natacha author non-byline.; Oederlin Nicolas author non-byline.; Pennacchio Francesco author non-byline.; Perez-Saez Javier author non-byline.; Petrovic Dusan author non-byline.; Picazio Attilio author non-byline.; Pittet Didier author non-byline.; Piumatti Giovanni author non-byline.; Portier Jane author non-byline.; Poulain Géraldine author non-byline.; Pugin Caroline author non-byline.; Pullen Nick author non-byline.; Rakotomiaramanana Barinjaka author non-byline.; Randrianandrasana Zo Francia author non-byline.; Richard Aude author non-byline.; Richard Viviane author non-byline.; Rodriguez-Velazquez Sabina author non-byline.; Salzmann-Bellard Lilas author non-byline.; Stringhini Silvia author non-byline.; Thorens Leonard author non-byline.; Torroni Simon author non-byline.; Trono Didier author non-byline.; Vidonne David author non-byline.; Violot Guillemette author non-byline.; Vuilleumier Nicolas author non-byline.; Waldmann Zoé author non-byline.; Will Manon author non-byline.; Wisniak Ania author non-byline.; Yerly Sabine author non-byline.; Zaballa María-Eugenia author non-byline.;
• Is Part Of: Occupational and environmental medicine. Volume 79:Issue 2(2022)
• Page Start: 116
• Page End: 119
• Publication Date: 2021-12-08
• Subjects: COVID-19 -- occupational health; Medicine, Industrial -- Periodicals; Environmental health -- Periodicals; 616.980305
• DOI: 10.1136/oemed-2021-107924
• Languages: English
• ISSNs: 1351-0711

Abstract

Abstract : Objectives: This cohort study including essential workers, assessed the risk and incidence of SARS-CoV-2 infection during the second surge of COVID-19 according to baseline serostatus and occupational sector. Methods: Essential workers were selected from a seroprevalence survey cohort in Geneva, Switzerland and were linked to a state centralised registry compiling SARS-CoV-2 infections. Primary outcome was the incidence of virologically confirmed infections from serological assessment (between May and September 2020) to 25 January 2021, according to baseline antibody status and stratified by three predefined occupational groups (occupations requiring sustained physical proximity, involving brief regular contact or others). Results: 10 457 essential workers were included (occupations requiring sustained physical proximity accounted for 3057 individuals, those involving regular brief contact, 3645 and 3755 workers were classified under 'Other essential occupations'). After a follow-up period of over 27 weeks, 5 (0.6%) seropositive and 830 (8.5%) seronegative individuals had a positive SARS-CoV-2 test, with an incidence rate of 0.2 (95% CI 0.1 to 0.6) and 3.2 (95% CI 2.9 to 3.4) cases per person-week, respectively. Incidences were similar across occupational groups. Seropositive essential workers had a 93% reduction in the hazard (HR of 0.07, 95% CI 0.03 to 0.17) of having a positive test during the follow-up with no significant between-occupational group difference. Conclusions: A 10-fold reduction in the hazard of being virologically tested positive was observed among anti-SARS-CoV-2 seropositive essential workers regardless of their sector of occupation, confirming the seroprotective effect of a previous SARS-CoV2 exposure at least 6 months after infection.