A Flexible Method for Covalent Double Functionalization of Graphene Oxide. (12th December 2019)

• Record Type: Journal Article
• Authors: Guo, Shi; Nishina, Yuta; Bianco, Alberto; Ménard‐Moyon, Cécilia
• Is Part Of: Angewandte Chemie. Volume 132:Number 4(2020)
• Page Start: 1558
• Page End: 1563
• Publication Date: 2019-12-12
• Subjects: Graphen -- Kleinringsysteme -- Materialwissenschaften -- Michael-Addition -- Oberflächenchemie; Chemistry -- Periodicals; 540
• DOI: 10.1002/ange.201913461
• Languages: English
• ISSNs: 0044-8249

Abstract

Abstract: A method for the double functionalization of graphene oxide (GO) under mild alkaline conditions has been developed. Two functional groups were covalently linked to GO in two steps: the first group was attached by an epoxide ring‐opening reaction and the second, bearing an amine function, was covalently conjugated to benzoquinone attached to the GO. The doubly functionalized GO was characterized by several techniques, confirming the sequential covalent modification of the GO surface with two different functional groups. This method is straightforward and the reaction conditions are mild, allowing preservation of the structure and properties of GO. This strategy could be exploited to prepare multifunctional GO conjugates with potential applications in many fields ranging from materials science to biomedicine. Abstract : Doppelt gekoppelt : Eine vielseitige Methode zur chemoselektiven doppelten Funktionalisierung von Graphenoxid wurde entwickelt. Sie umfasst a) eine Epoxidringöffnung durch ein geschütztes Aminoethanthiol, b) eine nachfolgende Reaktion der Hydroxygruppen mit Benzochinon und schließlich c) die Michael‐Addition eines Aminderivats.