Global burden of noncommunicable diseases attributable to high fasting plasma glucose. Issue 11 (8th August 2020)

• Record Type: Journal Article
• Authors: Ye, Lingxia; Xu, Jingya; Zhang, Tianyue; Lin, Xiling; Pan, Xiaowen; Zeng, Wenheng; Ren, Yuezhong; Shan, Pengfei
• Is Part Of: Journal of diabetes. Volume 12:Issue 11(2020)
• Page Start: 807
• Page End: 818
• Publication Date: 2020-08-08
• Subjects: fasting plasma glucose -- global burden of disease -- hyperglycemia -- noncommunicable diseases; 空腹血糖 -- 全球疾病负担 -- 高血糖 -- 非传染性疾病; Diabetes -- Periodicals; 618.3646005
• DOI: 10.1111/1753-0407.13072
• Languages: English
• ISSNs: 1753-0393

Abstract

Abstract: Background: Hyperglycemia is a major public health concern. An understanding of the latest trends of the global burden of noncommunicable diseases (NCDs) by high fasting plasma glucose (HFPG) is critical for determining research priorities and planning health policy. Methods: This is a comparative burden‐of‐disease study. We obtained global, regional, and national data on deaths and disability‐adjusted life years (DALYs) of NCDs attributable to HFPG from the Global Burden of Disease Study 2017, performed a secondary analysis of deaths and DALYs by time, age, gender, location, and specific causes, and analyzed their associations. Results: In 2017, 6.39 million deaths and 166.36 million DALYs from NCDs were attributable to HFPG, accounting for 15.6% and 10.7% of all deaths and DALYs, respectively. The burden's rate decreased with time, increased with age and was significantly higher in males. A negative association was found between the sociodemographic index (SDI) and disease burden, and a positive association was found between SDI and male superiority by gender difference and gender ratio. Conclusions: The burden of NCDs attributable to HFPG has increased significantly since 1990 and varied widely across regions. Greater efforts are needed to prevent and control hyperglycemia, especially in less developed countries and among males. Abstract : Highlights The burden of noncommunicable diseases (NCDs) attributable to high fasting plasma glucose (HFPG) has increased significantly since 1990. Men and the elderly have a heavier burden of NCDs caused by HFPG. A higher burden of HFPG was found to be associated with a lower sociodemographic index. 摘要: 背景: 高血糖是一个重大的公共健康问题。了解高空腹血糖导致的全球非传染性疾病负担的趋势变化对研究方向确定和卫生政策规划均有着重要作用。 方法: 这是一项关于疾病负担的对比研究, 通过从2017年全球疾病负担研究中获取全球、区域和民族的非传染性疾病死亡及伤残调整生命年(DALY)数据, 按照时间、年龄、性别、地区和特定疾病进行二次分析。 结果: 在2017年, 高空腹血糖导致的非传染性疾病共引起639万死亡和16 636万DALYs, 分别占全部死亡及DALY的15.6%和10.7%。校正年龄、人口后的疾病负担率随时间降低、随年龄增长, 且在男性中更高。此外, 疾病负担率还与社会人口指数存在显著负相关, 且该指数还与疾病负担率的男女差距呈显著正相关性。 结论: 高空腹血糖导致的非传染性疾病负担从20世纪90年代起显著增加, 且在不同地区间差异显著。对高血糖的预防和控制仍需更多努力, 尤其是在欠发达地区和男性中。