CD4 Response Up to 5 Years After Combination Antiretroviral Therapy in Human Immunodeficiency Virus-Infected Patients in Latin America and the Caribbean. (5th June 2015)

• Record Type: Journal Article
• Authors: Luz, Paula M.; Belaunzarán-Zamudio, Pablo F.; Crabtree-Ramírez, Brenda; Caro-Vega, Yanink; Hoces, Daniel; Rebeiro, Peter F.; Blevins, Meridith; Pape, Jean W.; Cortes, Claudia P.; Padgett, Denis; Cahn, Pedro; Veloso, Valdilea G.; McGowan, Catherine C.; Grinsztejn, Beatriz; Shepherd, Bryan E.
• Is Part Of: Open forum infectious diseases. Volume 2:Number 2(2015)
• Publication Date: 2015-06-05
• Subjects: cART -- cohort -- combination antiretroviral therapy -- HIV/AIDS -- immune recovery -- inverse probability of censoring weights -- Latin America and the Caribbean; Communicable diseases -- Periodicals; Medical microbiology -- Periodicals; Infection -- Periodicals; 616.9
• DOI: 10.1093/ofid/ofv079
• Languages: English
• ISSNs: 2328-8957

Abstract

Abstract : We describe CD4 counts at 6-month intervals for 5 years after combination antiretroviral therapy initiation among 12 879 antiretroviral-naive human immunodeficiency virus-infected adults from Latin America and the Caribbean. Median CD4 counts increased from 154 cells/mm 3 at baseline (interquartile range [IQR], 60–251) to 413 cells/mm 3 (IQR, 234–598) by year 5.