Pneumonia Mortality in Children Aged <5 Years in 56 Countries: A Retrospective Analysis of Trends from 1960 to 2012. (14th September 2017)

• Record Type: Journal Article
• Authors: Wu, Jie; Yang, Shigui; Cao, Qing; Ding, Cheng; Cui, Yuanxia; Zhou, Yuqing; Li, Yiping; Deng, Min; Wang, Chencheng; Xu, Kaijin; Ruan, Bing; Li, Lanjuan
• Is Part Of: Clinical infectious diseases. Volume 65:Number 10(2017)
• Page Start: 1721
• Page End: 1728
• Publication Date: 2017-09-14
• Subjects: pneumonia -- under-5 mortality -- trend analysis -- joinpoint regression; Communicable diseases -- Periodicals; 616.905
• DOI: 10.1093/cid/cix633
• Languages: English
• ISSNs: 1058-4838

Abstract

Abstract : An overall downward trend in pneumonia mortality in children aged &lt;5 years was observed in 56 countries between 1960 and 2012. However, the rate and absolute terms of decline differ by national income transition group. Abstract: Background: Pneumonia is now the second leading cause of death for children aged &lt;5 years worldwide. However, analyses of the long-term evolution of under-5 mortality from pneumonia are still scarce in the literature. We aimed to explore long-term trends of under-5 mortality from pneumonia in 56 countries from 1960 to 2012. Methods: Data on under-5 mortality from pneumonia were extracted from the World Health Organization mortality database. Long-term trends were assessed for 56 countries and for 4 national income transition groups. We also used joinpoint regression analysis to detect distinct period segments of long-term trends and estimate the annual percent of changes of each period segment. Results: The average mortality rate from pneumonia for children aged 0–4 years in 56 countries declined from 163.0 per 100000 children (95% confidence interval [CI], 119.4 to 212.8) in 1960 to 9.9 per 100000 children (95% CI, 6.4 to 13.4) in 2012, with an average annual percent of change of −5.6% (95% CI, −7.2% to −3.9%). The temporal trends of childhood mortality were different between national income transition groups. Conclusions: Our findings suggest a striking overall downward trend in under-5 mortality from pneumonia between 1960 and 2012. However, the rate and absolute terms of decline differ by national income transition group. These variable patterns between national income transition groups may inform further intervention setting and priority setting.