Diagnosis of Capnocytophaga canimorsus Sepsis by Whole-Genome Next-Generation Sequencing. (12th July 2016)

• Record Type: Journal Article
• Authors: Abril, Maria K.; Barnett, Adam S.; Wegermann, Kara; Fountain, Eric; Strand, Andrew; Heyman, Benjamin M.; Blough, Britton A.; Swaminathan, Aparna C.; Sharma-Kuinkel, Batu; Ruffin, Felicia; Alexander, Barbara D.; McCall, Chad M.; Costa, Sylvia F.; Arcasoy, Murat O.; Hong, David K.; Blauwkamp, Timothy A.; Kertesz, Michael; Fowler, Vance G.; Kraft, Bryan D.
• Is Part Of: Open forum infectious diseases. Volume 3:Number 3(2016)
• Publication Date: 2016-07-12
• Subjects: high-throughput nucleotide sequencing -- microbiological techniques -- sepsis/diagnosis; Communicable diseases -- Periodicals; Medical microbiology -- Periodicals; Infection -- Periodicals; 616.9
• DOI: 10.1093/ofid/ofw144
• Languages: English
• ISSNs: 2328-8957

Abstract

Abstract: We report the case of a 60-year-old man with septic shock due to Capnocytophaga canimorsus that was diagnosed in 24 hours by a novel whole-genome next-generation sequencing assay. This technology shows great promise in identifying fastidious pathogens, and, if validated, it has profound implications for infectious disease diagnosis.