Impact of Direct-Acting Antivirals on the Burden of HCV Infection Among Persons Who Inject Drugs and Men Who Have Sex With Men in the Swiss HIV Cohort Study. (26th June 2018)

• Record Type: Journal Article
• Authors: Salazar-Vizcaya, Luisa; Wandeler, Gilles; Fehr, Jan; Braun, Dominique; Cavassini, Matthias; Stoeckle, Marcel; Bernasconi, Enos; Hoffmann, Matthias; Rougemont, Mathieu; Béguelin, Charles; Rauch, Andri
• Is Part Of: Open forum infectious diseases. Volume 5:Number 7(2018)
• Publication Date: 2018-06-26
• Subjects: DAA -- HCV -- viral replication -- PWID -- MSM; Communicable diseases -- Periodicals; Medical microbiology -- Periodicals; Infection -- Periodicals; 616.9
• DOI: 10.1093/ofid/ofy154
• Languages: English
• ISSNs: 2328-8957

Abstract

Abstract: In the Swiss HIV Cohort Study, the number of people who inject drugs with replicating hepatitis C virus (HCV) infection decreased substantially after the introduction of direct-acting antivirals (DAAs). Among men who have sex with men, the increase in DAA uptake and efficacy was counterbalanced by frequent incident HCV infections.