Immune Control Despite Protracted Lymphopenia After Chemoradiation in an Elite Controller. (29th January 2016)

• Record Type: Journal Article
• Authors: Reiss, Kim A.; Jackson, Dvone C.; Piotrowski, Anna; Grossman, Stuart; Blankson, Joel N.
• Is Part Of: Open forum infectious diseases. Volume 3:Number 1(2016)
• Publication Date: 2016-01-29
• Subjects: elite suppressor -- elite controller -- treatment-related lymphopenia -- chemotherapy -- radiation therapy -- Human Immunodeficiency Virus -- small cell lung cancer; Communicable diseases -- Periodicals; Medical microbiology -- Periodicals; Infection -- Periodicals; 616.9
• DOI: 10.1093/ofid/ofw016
• Languages: English
• ISSNs: 2328-8957

Abstract

Abstract: Elite controllers are human immunodeficiency virus-1–positive individuals capable of sustaining undetectable viral loads without treatment. We present the case of an elite controller diagnosed with extensive stage small cell lung cancer who maintained a viral load of <20 copies/mL despite the development of severe treatment-related lymphopenia.