Breech at the Border: An Atypical Case of Invasive Haemophilus influenzae in a Patient on a Novel Immunotherapeutic. (26th June 2018)

• Record Type: Journal Article
• Authors: Howard-Anderson, Jessica; Satola, Sarah W; Collins, Matthew H
• Is Part Of: Open forum infectious diseases. Volume 5:Number 7(2018)
• Publication Date: 2018-06-26
• Subjects: Haemophilus influenzae -- interleukin-17 -- pelvic inflammatory disease -- pyosalpinx -- secukinumab; Communicable diseases -- Periodicals; Medical microbiology -- Periodicals; Infection -- Periodicals; 616.9
• DOI: 10.1093/ofid/ofy146
• Languages: English
• ISSNs: 2328-8957

Abstract

Abstract: Haemophilus influenza e rarely causes pyogenic infections in the female genital tract, and even less commonly does this lead to systemic infections. Novel monoclonal antibody therapies targeting interleukin-17 may impair mucosal immunity, but increased risk for H. influenza e infections has not been documented. Here, we describe a case of H. influenza e bacteremia associated with pyosalpinx and hypothesize that immunomodulatory treatment for psoriasis predisposed our patient to this infection.