Tailor made magnetic nanolights: fabrication to cancer theranostics applications. Issue 24 (1st November 2021)

• Record Type: Journal Article
• Authors: Das, Poushali; Ganguly, Sayan; Margel, Shlomo; Gedanken, Aharon
• Is Part Of: Nanoscale advances. Volume 3:Issue 24(2021)
• Page Start: 6762
• Page End: 6796
• Publication Date: 2021-11-01
• Subjects: 620.5
• DOI: 10.1039/d1na00447f
• Languages: English
• ISSNs: 2516-0230

Abstract

Abstract : This review covers the recent progress of magnetic nanolights, fabrication strategies, and application in cancer theranostics. Abstract : Nanoparticles having magnetic and fluorescent properties could be considered as a gift to materials scientists due to their unique magneto-optical qualities. Multiple component particles can overcome challenges related with a single component and unveil bifunctional/multifunctional features that can enlarge their applications in diagnostic imaging agents and therapeutic delivery vehicles. Bifunctional nanoparticles that have both luminescent and magnetic features are termed as magnetic nanolights. Herein, we present recent progress of magneto-fluorescent nanoparticles (quantum dots based magnetic nanoparticles, Janus particles, and heterocrystalline fluorescent magnetic materials), comprehensively describing fabrication strategies, types, and biomedical applications. In this review, our aim is not only to encompass the preparation strategies of these special types of magneto-fluorescent nanomaterials but also their extensive applications in bioimaging techniques, cancer therapy (targeted and hyperthermic), and sustained release of active agents (drugs, proteins, antibodies, hormones, enzymes, growth factors).