In-Hospital Pneumococcal Polysaccharide Vaccination Is Associated With Detection of Pneumococcal Vaccine Serotypes in Adults Hospitalized for Community-Acquired Pneumonia. (19th September 2015)

• Record Type: Journal Article
• Authors: Grijalva, Carlos G.; Wunderink, Richard G.; Zhu, Yuwei; Williams, Derek J.; Balk, Robert; Fakhran, Sherene; Courtney, D. Mark; Anderson, Evan J.; Qi, Chao; Trabue, Christopher; Pavia, Andrew T.; Moore, Matthew R.; Jain, Seema; Edwards, Kathryn M.; Self, Wesley H.
• Is Part Of: Open forum infectious diseases. Volume 2:Number 4(2015)
• Publication Date: 2015-09-19
• Subjects: antigen -- pneumococcal conjugate vaccine -- pneumonia -- serotype -- urine; Communicable diseases -- Periodicals; Medical microbiology -- Periodicals; Infection -- Periodicals; 616.9
• DOI: 10.1093/ofid/ofv135
• Languages: English
• ISSNs: 2328-8957

Abstract

Abstract: During an etiology study of adults hospitalized for pneumonia, in which urine specimens were examined for serotype-specific pneumococcal antigen detection, we observed that some patients received 23-valent pneumococcal polysaccharide vaccine before urine collection. Some urine samples became positive for specific vaccine pneumococcal serotypes shortly after vaccination, suggesting false-positive test results.