Asymptomatic Prenatal Zika Virus Infection and Congenital Zika Syndrome. (7th April 2018)

• Record Type: Journal Article
• Authors: Paixao, Enny S; Leong, Wei-Yee; Rodrigues, Laura C; Wilder-Smith, Annelies
• Is Part Of: Open forum infectious diseases. Volume 5:Number 4(2018)
• Publication Date: 2018-04-07
• Subjects: asymptomatic prenatal infection -- congenital Zika syndrome -- maternal infection -- microcephaly -- Zika; Communicable diseases -- Periodicals; Medical microbiology -- Periodicals; Infection -- Periodicals; 616.9
• DOI: 10.1093/ofid/ofy073
• Languages: English
• ISSNs: 2328-8957

Abstract

Abstract: To investigate to what extent asymptomatic vs symptomatic prenatal Zika virus infections contribute to birth defects, we identified 3 prospective and 8 retrospective studies. The ratio varied greatly in the retrospective studies, most likely due to recruitment and recall bias. The prospective studies revealed a ratio of 1:1 for asymptomatic vs symptomatic maternal Zika infections resulting in adverse fetal outcomes.