Anti-SARS-CoV-2 Antibody Level among Renal Transplant Recipients: A Case Report from Nepal. (10th January 2022)

• Record Type: Journal Article
• Authors: Ranabhat, Kamal; Saud, Bhuvan; Adhikari, Saroj; Bhattarai, Suraj; Adhikari, Rojan; Luitel, Bhoj Raj; Sigdel, Mahesh Raj
• Other Names: Chen Tun-Chieh Academic Editor.
• Is Part Of: Case reports in urology. Volume 2022(2022)
• Publication Date: 2022-01-10
• Subjects: Urology -- Periodicals; Urology -- Case studies -- Periodicals; Genitourinary organs -- Diseases -- Periodicals; Urologic Diseases; Genitourinary organs -- Diseases; Urology; Periodicals; Case studies; Periodicals; 616.6005
• DOI: 10.1155/2022/2889501
• Languages: English
• ISSNs: 2090-696X

Abstract

Abstract : Globally, SARS-CoV-2 has caused significant public health burden, mainly in patients with underlying comorbidities including both communicable and noncommunicable diseases. Solid organ transplant recipients under immunesupressive medication are also amongst the high risk group. There is only sparse data on immunity against SARS-CoV-2 infection among renal transplant recipients. In this case report, we present the level of anti-SARS-CoV-2 antibody of three kidney transplant recipients after vaccination against COVID-19 virus. All three cases had received two doses of Oxford-AstraZeneca COVID-19 vaccine AZD1222 (ChAdOx1). Serological analysis showed protective level of circulating antibodies in the blood of all three cases. Although two out of three patients in the study acquired COVID-19 infection after immunization, they recovered with mild clinical course. Hence, we conclude that despite immune-suppressed status of transplant recipients, COVID-19 vaccination could protect them against severe illness.