Ceftaroline in Combination With Trimethoprim-Sulfamethoxazole for Salvage Therapy of Methicillin-Resistant Staphylococcus aureus Bacteremia and Endocarditis. (8th July 2014)

• Record Type: Journal Article
• Authors: Fabre, Valeria; Ferrada, Marcela; Buckel, Whitney R.; Avdic, Edina; Cosgrove, Sara E.
• Is Part Of: Open forum infectious diseases. Volume 1:Number 2(2014)
• Publication Date: 2014-07-08
• Subjects: bacteremia -- ceftaroline fosamil -- MRSA -- salvage; Communicable diseases -- Periodicals; Medical microbiology -- Periodicals; Infection -- Periodicals; 616.9
• DOI: 10.1093/ofid/ofu046
• Languages: English
• ISSNs: 2328-8957

Abstract

Abstract: No clinical trials have investigated the use of ceftaroline fosamil for salvage therapy of methicillin-resistant Staphylococcus aureus bacteremia and endocarditis. We report data on 29 patients who received ceftaroline ± another antimicrobial for this indication. Ninety percent of patients had microbiologic cure and 31% had treatment success with a median follow-up of 6 months.