Acute Human Immunodeficiency Virus (HIV) Syndrome After Nonadherence to Antiretroviral Therapy in a Patient With Chronic HIV Infection: A Case Report. (23rd December 2014)

• Record Type: Journal Article
• Authors: Choi, Seong K.; Graber, Christopher J.
• Is Part Of: Open forum infectious diseases. Volume 1:Number 3(2014)
• Publication Date: 2014-12-23
• Subjects: acute HIV syndrome -- acute retroviral rebound syndrome -- chronic HIV infection -- nonadherence -- viral rebound; Communicable diseases -- Periodicals; Medical microbiology -- Periodicals; Infection -- Periodicals; 616.9
• DOI: 10.1093/ofid/ofu112
• Languages: English
• ISSNs: 2328-8957

Abstract

Abstract: We report a rare case of acute human immunodeficiency virus (HIV) syndrome in a patient with chronic HIV infection with acute illness indistinguishable from acute retroviral syndrome. The patient presented with an acute febrile mononucleosis-like illness after increasing nonadherence to antiretroviral therapy. A marked increase in HIV RNA level of 1 220 000 copies/mL from less than 20 copies/mL occurred within 3 weeks. The diagnosis of acute HIV syndrome was made after alternative causes of illness were ruled out.