Fertility‐Sparing Treatment of Endometrial Cancer with Initial Infiltration of Myometrium by Resectoscopic Surgery: A Pilot Study. (9th January 2018)

• Record Type: Journal Article
• Authors: Casadio, Paolo; Guasina, Francesca; Paradisi, Roberto; Leggieri, Concetta; Caprara, Giacomo; Seracchioli, Renato
• Is Part Of: Oncologist. Volume 23:Number 4(2018)
• Page Start: 478
• Page End: 480
• Publication Date: 2018-01-09
• Subjects: Oncology -- Periodicals; Tumors -- Periodicals; Cancérologie -- Périodiques; Tumeurs -- Périodiques; Oncology; Tumors; Neoplasms; Electronic journals; Periodicals; Periodicals; 616.994
• DOI: 10.1634/theoncologist.2017-0285
• Languages: English
• ISSNs: 1083-7159

Abstract

Abstract : Three women with a well‐differentiated grade 1 endometrioid adenocarcinoma of the endometrium with minimal myometrial infiltration were treated with hysteroscopic resection and hormone therapy. The presence of myometrial infiltration has often been mentioned as an exclusion criterion for conservative management in young patients because of worsening cancer prognosis. The subsequent 5‐year follow‐up and the pregnancies achieved may confirm the choice of this temporary treatment and indicate a new option for fertility‐sparing treatment in highly motivated patients. Abstract : A case series is presented of conservative, fertility‐sparing management of well‐differentiated G1 endometrioid adenocarcinoma of the endometrium with minimal infiltration of the myometrium, preventively treated with hysteroscopic resection and hormone therapy. This pilot study may offer a treatment option that preserves fertility in patients with superficial myometrial invasion.