Bacteremia and Septic Arthritis due to a Nontoxigenic Strain of Clostridium difficile in a Patient With Sickle Cell Disease. (2nd January 2018)

• Record Type: Journal Article
• Authors: Hill, Emilie; Workman, Adrienne D; Lee, Francesca; Hollaway, Rita; Cavuoti, Dominick; Prokesch, Bonnie C
• Is Part Of: Open forum infectious diseases. Volume 5:Number 2(2018)
• Publication Date: 2018-01-02
• Subjects: bacteremia -- Clostridium difficile -- hemoglobin SS disease -- septic arthritis -- sickle cell disease; Communicable diseases -- Periodicals; Medical microbiology -- Periodicals; Infection -- Periodicals; 616.9
• DOI: 10.1093/ofid/ofx278
• Languages: English
• ISSNs: 2328-8957

Abstract

Abstract: A 22-year-old female with sickle cell disease presented with fevers, bilateral knee pain, and lethargy. Laboratory data revealed a leukocytosis and lactic acidosis. Blood and synovial fluid cultures grew a non-toxin-producing strain of Clostridium difficile . This case highlights the fact that nontoxigenic Clostridium difficile can cause significant disease.