BNT162b2 Messenger RNA Vaccination Did Not Prevent an Outbreak of Severe Acute Respiratory Syndrome Coronavirus 2 Variant 501Y.V2 in an Elderly Nursing Home but Reduced Transmission and Disease Severity. (16th May 2021)

• Record Type: Journal Article
• Authors: Bailly, Benoit; Guilpain, Luc; Bouiller, Kevin; Chirouze, Catherine; N'Debi, Melissa; Soulier, Alexandre; Demontant, Vanessa; Pawlotsky, Jean-Michel; Rodriguez, Christophe; Fourati, Slim
• Is Part Of: Clinical infectious diseases. Volume 74:Number 3(2022)
• Page Start: 517
• Page End: 520
• Publication Date: 2021-05-16
• Subjects: SARS CoV-2 -- outbreak -- variant -- BNT162b2 vaccine -- nursing home; Communicable diseases -- Periodicals; 616.905
• DOI: 10.1093/cid/ciab446
• Languages: English
• ISSNs: 1058-4838

Abstract

Abstract: We report an outbreak of severe acute respiratory syndrome coronavirus 2 501Y.V2 in a nursing home. All nonvaccinated residents (5/5) versus half of those vaccinated with BNT162b2 (13/26) were infected. Two of 13 vaccinated versus 4 of 5 nonvaccinated residents presented severe disease. BNT162b2 did not prevent the outbreak, but reduced transmission and disease severity.