Retreatment of Chronic Hepatitis C Infection: Real-World Regimens and Outcomes From National Treatment Programs in Three Low- and Middle-Income Countries. (3rd July 2021)

• Record Type: Journal Article
• Authors: Boeke, Caroline E; Hiebert, Lindsey; Waked, Imam; Tsertsvadze, Tengiz; Sharvadze, Lali; Butsashvili, Maia; Zakalashvili, Mamuka; Naing, Win; Gupta, Neil; Kateera, Fredrick; McClure, Craig; Ward, John W; Ramers, Christian B
• Is Part Of: Clinical infectious diseases. Volume 74:Number 3(2022)
• Page Start: 513
• Page End: 516
• Publication Date: 2021-07-03
• Subjects: hepatitis C -- HCV -- retreatment -- treatment failure -- low- and middle-income countries; Communicable diseases -- Periodicals; 616.905
• DOI: 10.1093/cid/ciab461
• Languages: English
• ISSNs: 1058-4838

Abstract

Abstract: Access to recommended second-line treatments is limited for patients who fail initial hepatitis C virus (HCV) therapy in low- and middle-income countries. Alternative regimens and associated outcomes are not well understood. Through a pooled analysis of national program data in Egypt, Georgia, and Myanmar, we observed SVR rates >90% for alternative retreatment regimens.