The DISCUSS Project: Revised Points to Consider for the Derivation of Induced Pluripotent Stem Cell Lines From Previously Collected Research Specimens. (5th January 2015)

• Record Type: Journal Article
• Authors: Lomax, Geoffrey P.; Hull, Sara Chandros; Isasi, Rosario
• Is Part Of: Stem cells translational medicine. Volume 4:Number 2(2015)
• Page Start: 123
• Page End: 129
• Publication Date: 2015-01-05
• Subjects: Stem cells -- Periodicals; Regenerative medicine -- Periodicals; Periodicals; 616.0277405
• DOI: 10.5966/sctm.2014-0192
• Languages: English
• ISSNs: 2157-6564

Abstract

Abstract : The Deriving Induced Stem Cells Using Stored Specimens (DISCUSS) project is a consensus-building initiative designed to consider how human somatic cells obtained under general biomedical research protocols can be used in induced pluripotent stem cell (iPSC) derivation. This report presents a revised list of points to consider for the use of previously collected specimens in iPSC research, as well as a summary of published feedback of the previous version. Summary: Human somatic cell reprogramming is a leading technology for accelerating disease modeling and drug discovery. The Deriving Induced Stem Cells Using Stored Specimens (DISCUSS) project is a consensus-building initiative designed to consider how human somatic cells obtained under general biomedical research protocols can be used in induced pluripotent stem cell (iPSC) derivation. We previously published a draft list of points to consider for the use of previously collected specimens in iPSC research and then initiated a structured feedback and comment process. Here, we present a summary of this feedback and revised list of points to consider.