Primary Larynx Cryptococcus neoformans Infection: A Distinctive Clinical Entity. (26th October 2015)

• Record Type: Journal Article
• Authors: Bergeron, Mathieu; Gagné, Andrée-Anne; Côté, Mathieu; Chênevert, Jacinthe; Dubé, Robert; Pelletier, René
• Is Part Of: Open forum infectious diseases. Volume 2:Number 4(2015)
• Publication Date: 2015-10-26
• Subjects: Cryptococcus -- fluconazole -- fungal infection -- larynx -- vocal cords; Communicable diseases -- Periodicals; Medical microbiology -- Periodicals; Infection -- Periodicals; 616.9
• DOI: 10.1093/ofid/ofv160
• Languages: English
• ISSNs: 2328-8957

Abstract

Abstract: Cryptococcus neoformans can directly infect the vocal cords. Endoscopic findings were undistinctive from most infiltrative diseases. Tissue biopsy was essential for the diagnosis. Inhaled corticosteroids can predispose to the infection, and fluconazole 400 mg daily for at least 6 weeks appeared to be minimal to achieve a permanent cure.