Fatal Human Meningoencephalitis due to Halicephalobus Nematodes, Germany. (4th May 2015)

• Record Type: Journal Article
• Authors: Monoranu, Camelia-Maria; Müllges, Wolfgang; Keppler, Marc; Brehm, Klaus; Ondrejka, Sarah L.; Muntau, Birgit; Tannich, Egbert; Müller-Hermelink, Hans Konrad; Tappe, Dennis
• Is Part Of: Open forum infectious diseases. Volume 2:Number 2(2015)
• Publication Date: 2015-05-04
• Subjects: Halicephalobus -- horses -- meningoencephalitis -- nematode -- PCR; Communicable diseases -- Periodicals; Medical microbiology -- Periodicals; Infection -- Periodicals; 616.9
• DOI: 10.1093/ofid/ofv061
• Languages: English
• ISSNs: 2328-8957

Abstract

Abstract: Infections with Halicephalobus nematodes, causative agents of severe meningoencephalitis in horses, have rarely been reported in humans. In this study, the clinical, serological, cytokine, and histopathological findings of a rapidly progressive and eventually fatal meningoencephalitis in a previously healthy human are described. The helminth was finally diagnosed by specific polymerase chain reactions from post mortem tissue.