West Nile Virus Central Nervous System Infection in Patients Treated With Rituximab: Implications for Diagnosis and Prognosis, With a Review of Literature. (19th September 2015)

• Record Type: Journal Article
• Authors: Morjaria, Sejal; Arguello, Esther; Taur, Ying; Sepkowitz, Kent; Hatzoglou, Vaios; Nemade, Ajay; Rosenblum, Marc; Cavalcanti, Marcela S.; Palomba, M. Lia; Kaltsas, Anna
• Is Part Of: Open forum infectious diseases. Volume 2:Number 4(2015)
• Publication Date: 2015-09-19
• Subjects: immunocompromised host -- lymphoma -- molecular testing -- rituximab -- West Nile virus; Communicable diseases -- Periodicals; Medical microbiology -- Periodicals; Infection -- Periodicals; 616.9
• DOI: 10.1093/ofid/ofv136
• Languages: English
• ISSNs: 2328-8957

Abstract

Abstract: The spectrum of West Nile virus (WNV) infection continues to be elucidated. Many cases of WNV are asymptomatic; however, in immunocompromised patients, symptoms are more likely to be severe. We describe fatal WNV central nervous system disease in lymphoma patients who received rituximab, blunting the inflammatory response and complicating diagnosis.