Current advances in engineering cyanobacteria and their applications for photosynthetic butanol production. (February 2022)

• Record Type: Journal Article
• Authors: Liu, Xufeng; Xie, Hao; Roussou, Stamatina; Lindblad, Peter
• Is Part Of: Current opinion in biotechnology. Volume 73(2022)
• Page Start: 143
• Page End: 150
• Publication Date: 2022-02
• Subjects: Biotechnology -- Periodicals; 660.6
• DOI: 10.1016/j.copbio.2021.07.014
• Languages: English
• ISSNs: 0958-1669

Abstract

Graphical abstract: Highlights: Cyanobacteria can be engineered for chemical production from solar energy and CO2 . Recent progress has advanced cyanobacteria as green cell factories for production. Status of and prospects for photosynthetic butanol production are reviewed. Abstract : Cyanobacteria are natural photosynthetic microbes which can be engineered for sustainable conversion of solar energy and carbon dioxide into chemical products. Attempts to improve target production often require an improved understanding of the native cyanobacterial host system. Valuable insights into cyanobacterial metabolism, biochemistry and physiology have been steadily increasing in recent years, stimulating key advancements of cyanobacteria as cell factories for biochemical, including biofuel, production. In the present review, we summarize the current progress in engineering cyanobacteria and discuss the achieved and potential utilization of these advances in cyanobacteria for the production of the bulk chemical butanol, specifically isobutanol and 1-butanol.