Efficacy of Liuzijue Qigong in patients with chronic obstructive pulmonary disease: A systematic review and meta-analysis. (May 2022)

• Record Type: Journal Article
• Authors: Xu, Shuanglan; Zhang, Dandan; He, Quan; Ma, Chenhui; Ye, Sheng; Ge, Linyang; Zhang, Liuchao; Liu, Weihua; Chen, Zi; Zhou, Linfu
• Is Part Of: Complementary therapies in medicine. Volume 65(2022)
• Publication Date: 2022-05
• Subjects: AC airway conductance -- AR airway resistance -- 95% CI 95% confidence interval -- CAT COPD assessment test score -- COPD chronic obstructive pulmonary disease -- EPmax maximal expiratory pressure -- FEV1 forced expiratory volume in 1 s -- FEV1% percent predicted normal values of forced expiratory volume in 1 s -- FVC forced volume capacity -- HAMA Hamilton Anxiety Scale -- HAMD Hamilton Depression Scale -- IPmax maximal inspiration pressure -- 6MWD 6-min walking distance -- MD mean difference -- mMRC modified Medical Research Council -- MRC Medical Research Council -- PaCO2 partial pressure of carbon dioxide -- PaO2 partial pressure of oxygen -- RCT randomised controlled trial -- RR respiratory rate -- SpO2 peripheral capillary oxygen saturation -- 30-s SST 30-s sit-to-stand test -- SGRQ St. George's respiratory questionnaire -- TCM Traditional Chinese Medicine; Chronic obstructive pulmonary disease -- Liuzijue -- Qigong -- Meta-analysis; Alternative medicine -- Periodicals; Complementary Therapies -- Periodicals; Médecines parallèles -- Périodiques; Thérapeutique -- Périodiques; Alternative medicine; Electronic journals; Periodicals; 615.5
• DOI: 10.1016/j.ctim.2022.102809
• Languages: English
• ISSNs: 0965-2299

Abstract

Abstract: Background: Liuzijue is a traditional Qigong exercise that is commonly performed in China. However, the treatment effects of Liuzijue Qigong are controversial. The aim of this systematic review was to evaluate the efficacy of Liuzijue Qigong in patients with chronic obstructive pulmonary disease (COPD). Methods: Randomised controlled trials were identified by searching several English and Chinese databases from inception to August 8, 2020. Study selection and data extraction were independently performed by two investigators. Data synthesis and analysis were carried out with Review Manager software 5.2. Quality assessment for each study was based on the modified Jadad scale. Results: Forty studies with 3137 participants were included. Significant improvements were observed in the following outcomes (mean difference, 95% confidence interval): forced expiratory volume in 1 s (0.17, 0.09–0.25) and its percent predicted normal value (6.04, 3.43–8.65), forced expiratory volume in 1 s to forced volume capacity ratio (6.95, 3.06–10.83), 6-min walking distance (33.06, 23.73–42.38), 30-s sit-to-stand test (2.65, 0.98–4.32), COPD assessment test score (− 2.04, − 2.77 to − 1.30), modified Medical Research Council dyspnea scale (− 0.34, − 0.48 to − 0.20), Medical Research Council dyspnea scale (− 0.37, − 0.57 to − 0.18), Traditional Chinese Medicine syndrome score (− 1.85, − 2.86 to − 0.85), Hamilton Anxiety Scale (− 2.31, − 3.04 to − 1.59), Hamilton Depression Scale (− 2.08, − 2.45 to − 1.71) and St. George's Respiratory Questionnaire (− 6.94, − 9.20 to − 4.67). Conclusions: Liuzijue Qigong may be an effective adjuvant therapy for the improvement of lung function, exercise capacity, health status, mental status and quality of life in patients with COPD . Highlights: Forty articles were identified to evaluate the efficacy of Liuzijue Qigong in patients with chronic obstructive pulmonary disease (COPD). Liuzijue Qigong had positive effects on improving lung function, exercise capacity, health status, mental status, and quality of life in COPD patients. Liuzijue Qigong may be an effective adjuvant therapy for patients with COPD.