A novel rapid synthesis, characterization and applications of calcium phosphate nanospheres from Baltic seawater. Issue 8 (1st June 2018)

• Record Type: Journal Article
• Authors: Qin, Tao; Qin, Weiwei; Ma, Ming; Zhang, Dawei; Hu, Shugang; Zhang, Peng; Nikolajeff, Fredrik; Engqvist, Håkan
• Is Part Of: Ceramics international. Volume 44:Issue 8(2018)
• Page Start: 9076
• Page End: 9079
• Publication Date: 2018-06-01
• Subjects: Seawater -- Nanosphere -- Low cost -- Drug -- Calcium phosphate; Ceramics -- Periodicals; Céramique industrielle -- Périodiques; Ceramics; Periodicals; Electronic journals; 666
• DOI: 10.1016/j.ceramint.2018.02.114
• Languages: English
• ISSNs: 0272-8842

Abstract

Abstract: Due to the considerable high bio-compatibility, calcium phosphate nanoparticles are widely used in biomedical applications. This study proposes a novel strategy for low-cost manufacturing calcium phosphate nanoporous spheres. The controlled reaction only took less than five minutes, when using Baltic seawater with the dissolved calcium concentration of 2.2 mM as the calcium resources. Porous nanospheres were obtained, with spheres ranging from 50 to 130 nm. The obtained nanospheres possess high drug-loading capacity and exhibit sustained release and pH-dependent properties. In addition, this method provides a general efficient strategy to synthesize other low-cost inorganic nanospheres from seawater.