A phototoxic drug reaction due to topical NSAIDs. Issue 1 (20th January 2022)

• Record Type: Journal Article
• Authors: Drivenes, Jakob Lillemoen; Berg‐Jensen, Martin; Bygum, Anette
• Is Part Of: Clinical case reports. Volume 10:Issue 1(2022)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2022-01-20
• Subjects: dicloxacillin -- drug‐induced photosensitivity -- ketoprofen -- photoreaction -- photosensitivity -- phototoxic reaction; Medicine -- Periodicals; 616.09
• DOI: 10.1002/ccr3.5251
• Languages: English
• ISSNs: 2050-0904

Abstract

Abstract: We present a case with a phototoxic reaction following topical use of NSAID. The phototoxic reaction was initially mistaken for cellulitis which led to treatment with dicloxacillin, which led to an exanthematous drug eruption. The patient was treated with topical clobetasol propionate and oral non‐sedating antihistamines. Follow‐up revealed post‐inflammatory hypopigmentation. Abstract : Photosensitivity is uncommon, and a systematic approach and thorough assessment of medical history are essential for diagnosis. Avoidance of photosensitizing agents and use of ultraviolet protection can minimize risk of photosensitivity. Patients should be advised that some drugs carry greater risk of drug‐induced photosensitivity which necessitates avoidance of ultraviolet light.