Physiology of Tremor Reduction by Putting the Hands Together in Essential Tremor. Issue 2 (30th December 2021)

• Record Type: Journal Article
• Authors: McGurrin, Patrick; Vial, Felipe; Osterholt, Thomas; Norato, Gina; Khan, Imran; Haubenberger, Dietrich; Ehrlich, Debra; Hallett, Mark
• Is Part Of: Movement disorders clinical practice. Volume 9:Issue 2(2022)
• Page Start: 191
• Page End: 197
• Publication Date: 2021-12-30
• Subjects: essential tremor -- physiology -- tremor; Movement Disorders; Movement disorders -- Periodicals; Movement disorders; Periodicals; Periodicals; 616
• DOI: 10.1002/mdc3.13395
• Languages: English
• ISSNs: 2330-1619

Abstract

ABSTRACT: Background: Essential tremor is a common movement disorder, characterized by 4–12 Hz tremor of the hands and arms that can affect many activities of daily living. It has been reported by patients that when performing tasks bimanually their tremor is reduced, but why this happens is unknown. Objectives: We measured patients' tremors in different conditions when performed with 1 hand and 2 hands to observe if bimanual task performance changes the characteristics of the tremor. Methods: A total of 10 patients with essential tremor participated in the study. Electromyographic electrodes were attached bilaterally to the wrist flexor and extensor muscles, and accelerometers were attached to the dorsum of the hands. For each condition, holding a cup, wingbeat, and extending both arms up, data were collected with a single hand and bimanually with the hands touching. Results: When the hands were touching, there was a significant decrease in both accelerometric and electromyographic power at the tremor frequency. In addition, there was a decrease in coherence between accelerometer and electromyography on the same side. There was no change in the tremor frequency. Conclusions: Tremor amplitude does decrease when the hands are together. Together, the characteristics underlying the decrease in tremor amplitude may indicate a decrease in power of the central oscillator driving the tremor, which we speculate is attributed to the differences in unimanual and bimanual motor control. However, given the small sample size, we note that future hypothesis‐driven studies with an a priori power analysis will be required to further explore this phenomenon.