Primary cutaneous mucormycosis in a premature neonate treated conservatively with amphotericin B. Issue 1 (9th December 2021)

• Record Type: Journal Article
• Authors: Vittitow, Stephany L.; Rusu, Corina A.; Abubakar, Maryam O.; Burnsed, Jennifer; Gru, Alejandro A.; Zlotoff, Barrett J.
• Is Part Of: Pediatric dermatology. Volume 39:Issue 1(2022)
• Page Start: 99
• Page End: 102
• Publication Date: 2021-12-09
• Subjects: amphotericin B -- conservative treatment -- infant newborn diseases -- mucormycosis -- premature birth; Pediatric dermatology -- Periodicals; Children -- Diseases -- Periodicals; 618.925
• DOI: 10.1111/pde.14879
• Languages: English
• ISSNs: 0736-8046

Abstract

Abstract: Cutaneous mucormycosis is a rare, often fatal fungal infection that most commonly affects patients with underlying immunosuppression but also can occur in premature neonates. We report the case of an extremely premature boy (<25 weeks) who developed primary cutaneous mucormycosis shortly after birth. Although surgical debridement has been a mainstay of treatment in combination with antifungal therapy, our patient was successfully treated with amphotericin B alone—the management only reported in three other cases to date. We present this case to highlight that prompt initiation of treatment with amphotericin B alone may be an appropriate alternative to surgical intervention, particularly in patients with non‐angioinvasive disease who are poor surgical candidates.